By Allison Gilchrist, Associate Editor | pharmacytimes.com
A gay man has been infected with HIV despite taking Truvada every day for 2 years.
The case, which was reported by a scientist at the recent Conference on Retroviruses and Opportunistic Infections in Boston, is the first reported failure for pre-exposure prophylaxis (PrEP).
Truvada has been touted by both the US Centers for Disease Control and Prevention (CDC) and the World Health Organization as a highly reliable medication to lower the risk of HIV infection when taken consistently among those at high risk for transmission.
In the current case, pharmacy records and dried blood spot analysis both indicated “consistent dose-taking in the preceding 1 to 2 months,” noted David Knox, MD, an HIV specialist and lead author of the new study, during his presentation. The patient was reportedly “adamant” that he was completely adherent to PrEP since he first began the regimen in August 2013.
Dr. Knox also explained that the patient’s HIV-positive partner had “undetectable” levels of antiretroviral therapy, and he reported having anal sex without a condom within 2 to 6 weeks of testing positive for the infection. (Continue reading here.)
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